Progestin is a synthetic progesterone has an effect similar to natural progesterone. Progestin is a hormone and is used by both men and women for different purposes.
Progestins are prescribed for several reasons:
1. To properly regulate the menstrual cycle and stop trying unusual menstrual periods (amenorrhea). Progestins work by causing changes in the uterus.
After a series of drops of blood progesterone, the lining of the uterus starts to become part of and vaginal bleeding occurs (menstrual period). Progestins help other hormones start and stop the menstrual cycle.
2. To help pregnancy occur during egg donor or infertility procedures in women does not make enough progesterone. Progesterone is also provided to help maintain the pregnancy if the body is more capable.
3. To prevent the thickening of the uterine lining (endometrial hyperplasia) in postmenopausal women treated with estrogen for ovarian hormone therapy and ovarian hormone therapy (OHT).
4. To treat the pain associated with endometriosis, a condition where endometrial tissue lining of the uterus migrates to other female organs.
5. To treat a condition called endometriosis, to help prevent endometrial hyperplasia, or to treat abnormal bleeding, and weight of the uterus (dysfunctional uterine bleeding) by starting or stopping the menstrual cycle.
6. To help treat kidney cancer of the uterus, and breast. Progestins help change the ability of cancer cells respond to hormones and other proteins that cause tumor growth. In this way, progestins can stop tumor growth.
7. To verify that the body produces certain hormones, like estrogen.
8. To treat loss of appetite, severe weight loss and muscle weakness in patients with AIDS or cancer through the production of certain proteins that cause increased appetite and weight.
Progestins can also be used for other conditions as prescribed by your doctor. Progestins help other hormones work properly, helps prevent anemia (low iron levels in the blood), loss of blood due to menstruation, and uterine cancer. Progestins are available only by prescription.
POPs are also used in some patients with medical conditions as follows:
Carcinoma of prostate
The failure of the corpus luteum
Hot flashes, night sweats
Polycystic ovary syndrome
Adult or early puberty
Packaging
This product is available in tablet dosage form as, suspensions, capsules, gels, creams, and kits.
Dose
Medroxyprogesterone dosage forms of tablets:
1. For controlling abnormal bleeding and dysfunctional uterine bleeding or unusual treatment period (amenorrhea):
Adults and teenagers: 5 to 10 mg per day for 5-10 days as directed by your doctor.
2. To prepare the uterus during menstruation:
Adults and teenagers: 10 mg per day for five or ten days as directed by your doctor.
To prevent the thickening of the uterine lining (endometrial hyperplasia) when taking estrogen in ovarian hormone therapy in postmenopausal women:
1. Elderly: When taking estrogen each day from day one to day 25, 5 to 10 mg per day for 10-14 or more each month as directed by your doctor. Or your doctor may want the patient to drink 2.5 or 5 mg per day without stopping. Your doctor will help determine the number of pill is best for the patient and when to drink it.
Dosage form of an injection into the muscle
For the treatment of kidney or uterine cancer:
Adults and teenagers: First, 400-1000 mg injected into a muscle in a dose once a week. Then, your doctor may reduce the dose of 400 mg or more than once a month.
By injection under the skin dose:
To treat the pain of endometriosis:
Adults and teenagers: 104 mg injected under the skin of the thigh or abdomen every three months (12-14 weeks) not more than 2 years.
A megestrol suspension dosage forms:
To treat loss of appetite (anorexia), weakness (cachexia), or weight loss due to AIDS:
Adults and teenagers: 800 mg per day during the first month. Your doctor may want the patient to take 400 or 800 mg daily for three months.
A tablet dosage forms of megestrol:
For treatment of breast cancer:
Adults and teenagers: 160 mg per day in single dose or in divided doses for two months or more.
To treat uterine cancer:
Adults and children: 40-320 mg daily for two months or more.
To treat loss of appetite (anorexia), weakness (cachexia), or weight caused by cancer:
Adults and teenagers: 400-800 mg per day.
Norethindrone tablet dosage forms:
For controlling abnormal bleeding and dysfunctional uterine bleeding or stopping of menstrual periods that are not generic (amenorrhea):
Adults and teenagers: 2.5 to 10 mg per day from day 5 to day 25 (calculated from the first day of menstrual cycle). Your doctor may want the patient to take medication only 5-10 days.
To treat endometriosis:
Adults and teenagers: At first, 5 mg daily for two weeks. Your doctor may gradually increase the dosage to 15 mg daily for 6-9 months. Tell your doctor if the patient's menstrual period has begun. Your doctor may want the patient to drink more patients or to stop taking medication for a short time.
Progesterone capsule dosage form:
To prevent the thickening of the uterine lining (endometrial hyperplasia) when taking estrogen for ovarian hormone therapy in postmenopausal women:
Adults: 200 mg per day at bedtime for 12 consecutive days per cycle from 28 days of estrogen treatment each month.
For treatment of regular menstrual periods stop (amenorrhea):
Adults: 400 mg daily at bedtime for ten days.
Vaginal gel dosage forms:
To stop an unusual menstrual periods (amenorrhea):
Adults and teenagers: 45 mg once daily for six doses. The dose may be increased to 90 mg once daily for six doses if needed.
For use with infertility procedures:
Adults and teenagers: 90 mg once or twice a day. If pregnancy occurs, treatment may continue until 10-12 weeks.
Injection dosage form:
For controlling abnormal bleeding and dysfunctional uterine bleeding or stopping of menstrual periods that are not generic (amenorrhea):
Adults and teenagers: 5 to 10 mg per day injected into a muscle for 6-10 days. Your doctor may want patients to receive 100 or 150 mg injected into a muscle in one dose. Sometimes your doctor may want to take estrogen APSI. If the menstrual period begins, doctors advise patients to stop taking the drug.
Vaginal suppository dosage forms:
To maintain the pregnancy (at ovulation and early pregnancy):
Adults and teenagers: 25 mg to 100 mg (one suppository) inserted into the vagina once or twice a day before ovulation. Your doctor may want the patient to use the drug in eleven weeks.
Side Effects
Depending on the amount of progestin used, progestin can have different effects. For example, high doses of progesterone are necessary for women who want to continue the pregnancy, whereas low-dose progestogen can prevent a pregnancy occurs.
Other effects can lead to weight gain, increased body temperature, increase the milk-producing glands for breast and other parts of the uterus to maintain pregnancy.
The most common side effects are:
1. Increasing the amount of the monthly menstrual bleeding duration, light vaginal bleeding between menstrual periods, heavy vaginal bleeding between menstrual periods, or stopping of menstrual periods.
2. Symptoms of blood sugar, such as dry mouth, frequent urination, loss of appetite or unusual thirst.
Side effects are rarely encountered:
1. Mental depression
2. Rash
3. Unexpected increase milk flow
